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细胞名称:OSUMMER.7 Mouse NRAS-Mutant Melanoma Cell Line
货号:SCC451
规格:vial of ≥1X10⁶ cells/vial vial
应用:Cells are tested negative for infectious diseases by a Mouse Essential CLEAR Panel and have been found to be negative for all pathologies in this test.
Cells are verified to be of mouse origin and negative for interspecies contamination from rat, human, Chinese hamster, Golden Syrian hamster, and non-human primate (NHP) as assessed by a Contamination Clear panel.
Cells are negative for mycoplasma contamination.
Cells are genotyped by STR analysis to verify the unique identity of the cell line.
特点和优势:The OSUMMER.7 melanoma cell line carries the NRAS mutation Q61R and may be used to create syngeneic mouse melanoma models.
储存及稳定性:Cells should be stored in liquid nitrogen. Cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.
其他说明:This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation.
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文献和实验through six litters before deciding to give up on it. If a chimera has a high transmission ratio, you should consider mating it directly with females from the 129 mouse strain that matches the origin of the ES cell line to obtain your targeted gene mutation
represents a somewhat surreal over-expression of a given protein often causing spurious phenotypes. The generation of conditional knockout mice is a multiple-step process, which involves mating the flox mutant mouse line (essential exon/s of the gene
In Vitro Mouse Lymphoma Forward Mutation Assay
The in vitro mouse lymphoma assay (MLA) is one of the most widely practiced assays in genetic toxicology. MLA detects forward mutations at the thymidine kinase (Tk ) locus of the L5178Y (Tk +/− -3.7.2C) cell line derived from a mouse thymic










