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文献和实验Quantitation of Major Histocompatibility Complex Antigen Endocytosis Using Capture ELISA
Major histocompatibility class I and II (MHC-I and MHC-II) antigens (Ags), as well as a variety of cell surface receptors, have been shown to enter the endocytic pathway of antigen-presenting cells (APCs). MHC Ags endocytose into clathrin
The INK4a/ARF Locus and Human Cancer
This review focuses on the role of the INK4a/ARF locus in human cancer. Several excellent related reviews have recently been published (1 –5 ). Rather than presenting protocols, this review will describe the current state of the field
Methods for Human CD8+ T Lymphocyte Proteome Analysis
T lymphocytes, including cytotoxic CD8+ T cells, are important cells involved in immunology, as they can destroy infected or tumor cells. We describe here a detailed protocol starting from CD8+ T lymphocytes isolation for T cell culture followed
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