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文献和实验Chimeric Antigen Receptors for T-Cell Based Therapy
The Chimeric Antigen Receptor (CAR) consists of an antibody-derived targeting domain fused with T-cell signaling domains that, when expressed by a T-cell, endows the T-cell with antigen specificity determined by the targeting domain
MicroRNA Expression Profiling During Neural Differentiation of Mouse Embryonic Carcinoma P19 Cells
The Mouse P19 cell line was derived from an embryonal carcinoma. The pluripotent P19 cells can be induced to differentiate into neuronal and glial cells. Here, we describe an miRNA microarray method to monitor the miRNA expression profiles
The Purification of Large Numbers of Antigen Presenting Dendritic Cells from Mouse Spleen
-tolerance. A key element in the ability of DC to initiate adaptive immune responses is their capacity to capture and process antigen, whether from pathogens, vaccines or self-components, and present it to T cells. Our typical procedure for isolation
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