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文献和实验of the growth fraction. Proliferating cell nuclear antigen (PCNA) is an endogenous nuclear protein that functions as an accessory protein to DNA polymerase (pol) δ (1 ). Since PCNA is present in all cycling cells, the entire proportion of dividing cells present
Proliferating cell nuclear antigen (PCNA) is a homotrimeric protein adopting a ring structure that may encircle DNA. In this form, PCNA functions as a sliding platform to which different types of catalytic and regulatory proteins are tethered
Isolation of Human Tumor-Associated Cell Surface Antigen-Binding scFvs
Several approaches have been used to identify antibody (Ab)-defined human tumor-associated antigens (TAA) that can be used for passive and/or active specific immunotherapy of malignant diseases. For example, hybridoma technology
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