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文献和实验The Use of Connexin-Based Therapeutic Approaches to Target Inflammatory Diseases
Alterations in Connexin43 (Cx43) expression levels have been shown to play a role in inflammatory processes including skin wounding and neuroinflammation. Cx43 protein levels increase following a skin wound and can inhibit wound healing
【进展|热点】Nature Immunology：骨髓基质细胞通过细胞间接触分泌SDF-1
dependent event mediated by connexin-43 (Cx43) and Cx45 gap junctions. Inhibition of connexin gap junctions impaired the secretion of CXCL12 and homing of leukocytes to mouse bone marrow. Purified human CD34+ progenitor cells did not adhere to noncontacting
Vascular Connexins in Restenosis After Balloon Injury
and thrombus formation, animal models have been developed. In this chapter, we describe the experimental model of balloon injury adapted for mice and apply it to study the role of Cx43 in this process. Connexins are members of a large family of transmembrane
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