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文献和实验CGG CTG TCT TCA C TSC-2-829 CAA GGA GGT TCC GCA TCA G APC-5846 ATG ACT GGG GAA AAG TGG ATT GT APC-1797 ATA CGC TTT
Purification of the Mitotic Checkpoint Complex, an Inhibitor of the APC/C From HeLa Cells
The mitotic checkpoint prevents cells with unaligned chromosomes from prematurely exiting mitosis by inhibiting the anaphase-promoting complex/cyclosome (APC/C) from targeting key proteins for ubiquitin-mediated proteolysis. Great efforts
In Vitro Assays for the Anaphase-Promoting Complex/Cyclosome (APC/C) in Xenopus Egg Extracts
The anaphase-promoting complex/cyclosome (APC/C), a large (20S) multisubunit E3 ligase, has an essential role to ubiquitylate numerous substrates at specific times during mitosis and G1 phase as well as in meiosis. The deregulation of the APC/C
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