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- DIMA BIOTECH/缔码生物
- 武汉
- PME48424
- 2025年07月12日
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- 保存条件：
-80°C
- 保质期：
请咨询
- 英文名：
Human PITX2 (NM_153426) Protein
- 库存：
1 week
- 供应商：
缔码生物（武汉）科技有限公司
- 规格：
50 ug
| 产品类别 | ECD Proteins |
|---|---|
| 靶点 | PITX2 |
| Uniprot ID | Q99697 |
| 背景 | This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
| 描述 | Purified recombinant protein of Human paired-like homeodomain 2 (PITX2), transcript variant 2, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug |
| 分子量 | 63.2 kDa |
| 纯度 | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| 别名 | ARP1; ASGD4; Brx1; IDG2; IGDS; IGDS2; IHG2; IRID2; Otlx2; PTX2; RGS; RIEG; RIEG1; RS |
| 标签 | N-GST and C-His |
| 表达宿主 | E. coli |
| 组分与重悬 | 25mM Tris, pH8.0,150mM NaCl,10% glycerol,1%Sarkosyl. |
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