- 询价
- DIMA BIOTECH/缔码生物
- 武汉
- FLP120167
- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C to -80°C
- 保质期：
12个月
- 英文名：
Human 5HT2B-Strep full length protein-synthetic nanodisc
- 库存：
6~8weeks
- 供应商：
缔码生物（武汉）科技有限公司
- 规格：
10μg
| 货号 | FLP120167 |
|---|---|
| 产品分类 | Full Length Transmembrane Proteins |
| 价格&规格 | Price: 10 μg ￥5670.00 ;50 μg ￥27000.00 ; 100 μg ￥49500.00 |
| 背景 | This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016] |
| 描述 | Human 5HT2B-Strep full length protein-synthetic nanodisc |
| 分子量 | The human full length 5HT2B-Strep protein has a MW of 54.3 kDa |
| 蛋白家族 | Transmembrane,Druggable Genome, |
| 信号通路 | GPCRDB Class A Rhodopsin-like,Monoamine GPCRs, |
| 别名 | 5-HT(2B), 5-HT-2B, 5-HT2B |
| 标签 | C-Flag&Strep Tag |
| 是否偶联 | Unconjugated |
| 表达宿主 | HEK293 |
| 形式 | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for |
| 靶点 | 5HT2B |
| Uniprot ID | P41595 |
| 用途 | Research use only |
验证图
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文献和实验Characterization of 5‐HT1A,B and 5‐HT2A,C Serotonin Receptor Binding
., Morse, B., Whitman, M.M., Ivanshchenko, Y., Jaye, M., and Felder, S. 1991. Cloning of the human serotonin 5‐HT2 and 5‐HT1C receptor subtypes. Biochem. Biophys. Res. Commun. . 181:1469‐1478.
gene encoding apolipoprotein B (apoB) after intravenous injection in mice. Administration of chemically modified siRNAs resulted in silencing of the apoB messenger RNA in liver and jejunum, decreased plasma levels of apoB protein, and reduced total
of m e m b r an e-b o u n d B ak -B cl-x L p r o te in sin vitro. Protein Eng. Des. SeL 1 7 , 501 -508.
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