7-Acetoxy-4-methylcoumarin

羧酸酯酶和乙酰胆碱酯酶的荧光底物；经羧酸酯酶或乙酰胆碱酯酶水解后，释放出4-MU，其在pH为4.6、7.4和10.4时分别显示出330、370和385nm的pH依赖性激发最大值，以及445-454nm之间的最大发射值；已用于检测分离的人体肺组织中羧酸酯酶的存在。A fluorogenic substrate for carboxylesterase and AChE; upon hydrolysis by carboxylic esterase or AChE, 4-MU is released, which displays pH-dependent excitation maxima of 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively, and an emission maximum between 445-454 nm; has been used to detect the presence of carboxylesterases in isolated human lung tissue.分子式C12H10O4分子量218.2O=C1OC2=C(C(C)=C1)C=CC(OC(C)=O)=C2