S1H (trifluoroacetate salt)

人类生长激素受体的合成肽拮抗剂；在100和200nM浓度下，可降低SK-MEL-28和MALME-3M细胞系中人类生长激素诱导的STAT5磷酸化，以及IM-9B细胞中催乳素诱导的STAT5磷酸化。A synthetic peptide antagonist of the human growth hormone receptor; decreases STAT5 phosphorylation induced by human growth hormone in SK-MEL-28 and MALME-3M cell lines, as well as by prolactin in IM-9 B cells, at 100 and 200 nM.分子式C94H141N23O27 • XCF3COOH分子量2025.3NC([C@@]([C@@H](C)O)([H])NC([C@H](CCC(N)=O)NC([C@@H]1CCCN1C([C@H](CC(N)=O)NC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CO)NC([C@@H](NC([C@H](CCCCN)NC([C@H](CCC(N)=O)NC([C@H](CCC(O)=O)NC([C@H](CCCCN)NC([C@@H]2CCCN2C([C@@]([C@H](CC)C)([H])NC([C@@H](NC(C)=O)CC3=CC=C(O)C=C3)=O)=O)=O)=O)=O)=O)=O)CC4=CC=C(O)C=C4)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O