IRBP (651-670) (human) (triflu

实验性自身免疫性葡萄膜视网膜炎的肽诱导剂；已用于诱导C57BL/6小鼠的自身免疫性葡萄膜视网膜炎；以300µg/只的剂量接种IRBP651-670可增加小鼠眼部IL-1β、IL-6、IL-17、TNF-α和IFN-γ水平、免疫细胞浸润和感光细胞损伤。A peptide inducer of experimental autoimmune uveoretinitis; has been used to induce autoimmune uveoretinitis in C57BL/6 mice; immunization with IRBP651-670 increases ocular IL-1β, IL-6, IL-17, TNF-α, and IFN-γ levels, immune cell infiltration, and photoreceptor damage in mice at 300 µg/animal.分子式C91H151N25O32 • XCF3COOH分子量2107.3CC(C)C[C@@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(NCC(N[C@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@@H](CCCNC(N)=N)C(N[C@]([C@H](O)C)([H])C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@@H](CO)C(N[C@H](C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@]([C@H](O)C)([H])C(O)=O)=O)CC(C)C)=O)=O)=O)C)=O)CC(C)C)=O)=O)=O)CC(C)C)=O)=O)=O)C)=O)=O)=O)=O)C)=O)=O)=O)C)=O)N[H].OC(C(F)(F)F)=O