Perfluorododecanoic Acid

一种全氟烷基物质；浓度为100µM时降低PC12细胞活力；浓度为100µM时增加ROS和MDA水平并降低PC12细胞中的线粒体膜电位；产前暴露与头围呈负相关；孕妇血清水平与妊娠期糖尿病呈正相关；已在湖鳟鱼(S.namaycush)中发现。A perfluoroalkyl substance; decreases the viability of PC12 cells at 100 µM; increases ROS and MDA levels and reduces the mitochondrial membrane potential in PC12 cells at 100 µM; prenatal exposure is negatively associated with head circumference; maternal serum levels are positively associated with gestational diabetes; has been found in lake trout (S. namaycush).分子式C12HF23O2分子量614.1O=C(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(F)F)F)F)F)F)F)F)F)F)F)F)O