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- 爱必信(Absin)
- 中国
- abs6114563
- 2025年07月13日
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文献和实验Generation and Analysis of Brca1 Conditional Knockout Mice
in breast cancer formation. Cre-loxP-mediated tissue-specific knockout was employed to overcome this obstacle. We found that the presence of a ploxP-neo -loxP cassette in intron 10 of Brca1 resulted in severe interference with gene expression. The neo
Gene Knockout Techniques(1) The Knockout Process
for mutations in unc-22Day 8 (Wednesday) unc-22 is a large gene that makes a good test target for mutagenesis. Mutations that knock out unc-22 produce a dominant "twitching" phenotype when the animals are exposed to 1% nicotine. The presence of twitchers
Ovarian Cancer Gene Therapy with BRCA1An Overview
The human breast and ovarian cancer susceptibility gene BRCA1 is a tumorsuppressor gene which is mutated and lost in hereditary breast and ovarian cancer, and has both alleles mutated in approximately 10-15% of cases of sporadic ovarian cancer
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