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文献和实验Gene Knockout Techniques(1) The Knockout Process
for mutations in unc-22Day 8 (Wednesday) unc-22 is a large gene that makes a good test target for mutagenesis. Mutations that knock out unc-22 produce a dominant "twitching" phenotype when the animals are exposed to 1% nicotine. The presence of twitchers
Radiation Hybrid (RH) Mapping of Human Smooth Muscle-Restricted Genes
Recent molecular genetic studies in cardiac and skeletal muscle have revealed mutations in a battery of sarcomeric muscle-restricted genes that appear to be associated with various myopathies (1 ,2 ). In sharp contrast, no mutations
and Feng Zhang Abstract The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 system is an adaptive immune system that exists in a variety of microbes. It could be engineered to function in eukaryotic cells as a fast, low-cost
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