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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Short term 4℃; Long term -20℃.
- 保质期:
见COA
- 英文名:
Recombinant Biotinylated Human LAP (TGF beta 1) , Avi-His-tag
- 库存:
大量
- 供应商:
北京辰辉创聚生物技术有限公司
- 规格:
100ug;1mg;Bulk

| 产品信息
品名:NebuSelect™ Recombinant Biotinylated Human LAP (TGF beta 1) , Avi-His-tag
货号:NBL-242381
品牌:Nebulabio
规格:100ug;1mg;Bulk
| 产品描述
NebuSelect™ Recombinant Biotinylated Human LAP (TGF beta 1) , Avi-His-tag(Cat#NBL-242381) is expressed in HEK293 with His tag and Avi tag at the N-Terminus.It contains Leu30-Arg278(C33S).
| 产品属性
表达系统:HEK293
标签:Avi-His-tag
靶点名称:LAP (TGF beta 1)
物种:Human
分子量:The protein has a predicted MW of 31.4 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Bis-Tris PAGE result.
氨基酸序列:
Accession: P01137
纯度:>95%
内毒素:<1EU/ug(LAL Method)
储存运输条件: Short term 4℃; Long term -20℃.
| 靶点信息
Latent TGF beta 1 cDNA encodes a 390 amino acid precursor that contains a 29 aa signal peptide and a 361 aa proprotein. A furin‑like convertase processes the proprotein to generate an N‑terminal 249 aa latency‑associated peptide (LAP) and a C‑terminal 112 aa mature TGF‑ beta 1. Disulfide‑linked homodimers of LAP and TGF‑ beta 1 remain non‑covalently associated after secretion, forming the small latent TGF‑ beta 1 complex.
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文献和实验一、转化生长因子-β(TGF-β) 转化生长因子-β(transforming growth factor-β,TGF-β)是属于一组新近发现的调节细胞生长和分化的TGF-β超家族。这一家族除TGF-β外,还有活化素(activins)、抑制素(inhibins)、缪勒氏管抑制质(Mullerian inhibitor substance,MIS)和骨形成蛋白(bone morpho-genetic proteins,BMPs
2 (1) M94362 1457-1479 aagaggaggaggaagccgagt Human HeLa LAP
ATGTTAAGACTAAGCATGTAC Xenopus embryo cytoplasmic dynein 1 heavy chain (1) U53530 509-531 aaggccaaggaggcgctggaa Human HeLa DIP13-alpha (DCC interacting protein) (25) AAGUGCAGCAACACACCUGAC DLD1 DIP13-beta (DCC interacting protein) (25) AAGCAGCACCUCUCCUCCCUU DLD
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