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Anti-YAP1 Recombinant Rabbit M

onoclonal Ab
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  • ¥860
  • Elucigen Biosciences
  • ERB0046
  • 2025年08月13日
  • ICC, IHC, WB
  • Rabbit
  • Human, Mouse
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Recombinant protein corresponding to the C-terminal region of human YAP1.

    • 亚型

      IgG

    • 形态

      Liquid

    • 保存条件

      -20°C

    • 克隆性

      Monoclonal

    • 标记物

      Unconjugated

    • 适应物种

      Human, Mouse

    • 保质期

      12 months from the shipping date of the product.

    • 抗原来源

      Human

    • 目录编号

      ERB0046

    • 级别

      Primary Antibodies

    • 库存

      Available

    • 供应商

      Elucigen Biosciences

    • 宿主

      Rabbit

    • 应用范围

      ICC, IHC, WB

    • 浓度

      0.5 mg/mL

    • 靶点

      P46937

    • 抗体英文名

      Anti-YAP1 Recombinant Rabbit Monoclonal Ab

    • 抗体名

      Anti-YAP1 Recombinant Rabbit Monoclonal Ab

    • 规格

      25μg/100μg/500μg

    规格:25μg产品价格:¥860.0
    规格:100μg产品价格:询价
    规格:500μg产品价格:询价
    YAP1 (Yes-associated protein 1) is a key transcriptional co-activator that regulates gene expression in response to mechanical cues and cellular stress, playing a central role in the Hippo signaling pathway. YAP1 controls cell proliferation, differentiation, and survival by interacting with transcription factors to activate genes involved in growth and development. When the Hippo pathway is inactive, YAP1 is dephosphorylated and translocates to the nucleus, where it promotes the expression of genes that drive cell growth and tissue regeneration. In contrast, when the Hippo pathway is active, YAP1 is phosphorylated and retained in the cytoplasm, inhibiting its activity. Dysregulation of YAP1 is implicated in various diseases, particularly cancer, where its overactivation can contribute to tumorigenesis by promoting unchecked cell growth and tissue invasion.

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    图标文献和实验
    该产品被引用文献
    Yu, F.X. et al. (2012) Cell 150, 780-91.
    相关实验
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    • Flow Cytometric Analysis Of Bcl Family members

      was analyzed using CELLQUEST software. Live cells were gated on the basis of forward and side scatter and a minimum of 10,000 events were analyzed. Recipes The primary antibodies used were mouse monoclonal AB against Bcl-2 (Dako, USA), rabbit polyclonal

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    文献支持
    Anti-YAP1 Recombinant Rabbit Monoclonal Ab
    ¥860