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- 技术资料
- 保存条件：
-20°C
- 保质期：
咨询
- 英文名：
8-pCPT-2-O-Me-cAMP-AM
- 库存：
1000+
- 供应商：
上海维亦特生物
- CAS号：
1152197-23-3
纯度：97% by HPLC
分子式：C20H21ClN5O8PS
分子量：557.91
溶剂：DMSO (50 mg/ml)
性状：solid
存储：-20°C
Activity (short version)：Epac activator
Function / Pharmacology：A potent, cell-permeable Epac (exchange protein directly activated by cAMP) activator1. Induces RAP1 activation and insulin secretion in pancreatic beta cell lines2-5. Induces vascular relaxation in rat mesenteric artery6. The acetoxymethyl ester confers increased cell-permeability and is cleaved by endogenous esterases to yield the active compound, 8-pCPT-2'-O-Me-cAMP. Addition to cell cultures should be done in serum-free media as esterases in serum will cleave the acetoxymethyl ester and reduce cell permeability.
分子式：C20H21ClN5O8PS
分子量：557.91
溶剂：DMSO (50 mg/ml)
性状：solid
存储：-20°C
Activity (short version)：Epac activator
Function / Pharmacology：A potent, cell-permeable Epac (exchange protein directly activated by cAMP) activator1. Induces RAP1 activation and insulin secretion in pancreatic beta cell lines2-5. Induces vascular relaxation in rat mesenteric artery6. The acetoxymethyl ester confers increased cell-permeability and is cleaved by endogenous esterases to yield the active compound, 8-pCPT-2'-O-Me-cAMP. Addition to cell cultures should be done in serum-free media as esterases in serum will cleave the acetoxymethyl ester and reduce cell permeability.
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文献和实验该产品被引用文献
1152197-23-3
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8-pCPT-2-O-Me-cAMP-AM
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