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- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
咨询
- 英文名：
Honokiol
- 库存：
1000+
- 供应商：
上海维亦特生物
- CAS号：
35354-74-6
纯度：>98% TLC/GC
NMR (Conforms)
分子式：C18H18O2
分子量：266.34
溶剂：DMSO (50 mg/ml)
性状：Beige solid
存储：-20°C
Activity (short version)：SIRT3 activator
Function / Pharmacology：Honokiol is a natural product that acts as a SIRT3 activator. It increases mitochondrial oxygen consumption and reduces ROS production in wild type but not SIRT3-KO cells.1 It reversed cardiac hypertrophy in mice1 and rescued myocardial and mitochondrial energetics in type 2 diabetic rats2. It was shown to increase SIRT3 expression in the hippocampus and attenuated surgery-induced memory loss, neuronal apoptosis, neuroinflammation and oxidative damage.3 It increases expression of adipocyte gene markers, gene-involved lipolysis and glucose transport and in general, promotes insulin sensitivity.4
分子式：C18H18O2
分子量：266.34
溶剂：DMSO (50 mg/ml)
性状：Beige solid
存储：-20°C
Activity (short version)：SIRT3 activator
Function / Pharmacology：Honokiol is a natural product that acts as a SIRT3 activator. It increases mitochondrial oxygen consumption and reduces ROS production in wild type but not SIRT3-KO cells.1 It reversed cardiac hypertrophy in mice1 and rescued myocardial and mitochondrial energetics in type 2 diabetic rats2. It was shown to increase SIRT3 expression in the hippocampus and attenuated surgery-induced memory loss, neuronal apoptosis, neuroinflammation and oxidative damage.3 It increases expression of adipocyte gene markers, gene-involved lipolysis and glucose transport and in general, promotes insulin sensitivity.4
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文献和实验该产品被引用文献
35354-74-6
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