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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 库存:
5
- 英文名:
Hypoxyprobe-Red549 Kit (100 mg pimonidazole HCl plus 1 unit of 4.3.11.3 Rat Dylight™549-MAb)
- CAS号:
详询
- 保质期:
详询
- 供应商:
北京孚博生物科技有限公司
- 保存条件:
未知
- 规格:
100mg
Hypoxyprobe-Red549 Kit (100 mg pimonidazole HCl plus 1 unit of 4.3.11.3 Rat Dylight™549-MAb)
Item# HP7-100Kit
$398.00
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文献和实验Hypoxyprobe, Inc. is a small company dedicated to providing tools for the diagnosis and treatment of malignant and normal tissue diseases in which oxygen regulation is disturbed. The company is located at 121 Middlesex Turnpike, Burlington, Massachusetts, USA 01803 and is a spin-off of the Hypoxyprobe Division of Natural Pharmacia International, Inc. (NPI).
Hypoxyprobe, Inc. arose from a collaboration between Dr. James Raleigh in the Department of Radiation Oncology at the University of North Carolina at Chapel Hill and NPI which at the time was located in the Research Triangle Park, North Carolina.
The collaboration between UNC Chapel Hill and NPI at first focused on clinical studies of tumor hypoxia. NPI manufactured pimonidazole HCl on a large scale and Dr. Raleigh provided patented antibody reagents for detecting the binding of pimonidazole to hypoxic cells in human tumors.
Preclinical studies in dogs, rats and mice generated a growing interest among the scientific community in pimonidazole HCl as a hypoxia marker in general and in 2002 NPI issued a five-year exclusive license to Chemicon International to market a limited line of Hypoxyprobe reagents for animal use. In 2006, anticipating a need for an expanded line of Hypoxyprobe reagents, NPI ended Chemicon’s license and established Hypoxyprobe, Inc. to develop an enhanced line of reagents for both animal and clinical studies.
The Company is now focused on developing non-invasive hypoxia markers and hypoxia dependent cytotoxins based on the pimonidazole core structure.
Studies of the Ubiquitin Proteasome System
6.1 ), and autoradiography (unit 6.3 ). Basic Protocol 6: Ubiquitylation of E3 Enzymes Expressed in In Vitro Translation Systems Materials 50 mM MG132 (Calbiochem, Boston Biochem, or BioMol) in DMSO 30 µM ubiquitin
LINEAGE ANALYSIS USING RETROVIRAL VECTORS
each) in the lavage solution. We have not had difficulty with infection using these techniques.MaterialsKetamine HCI injection (100 mg/ml ketamine)Xylazine injection (20 mg/ml)Animal support platformDepilatory Scalpel and disposable sterile bladesCotton swabs
Measurement of Oxygen Radicals and Lipid Peroxidation in Neural Tissues
) 10 mM HCl, ice cold Oxidized glutathione (GSSG) 5 mg/ml OPA solution (see recipe
技术资料




