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文献和实验shRNA-Induced Interferon-Stimulated Gene Analysis
identification and validation. In addition, small interfering RNA (siRNA) and short-hairpin RNA (shRNA) therapies are being developed for the treatment of a variety of human diseases. Despite its huge potential for gene silencing, a hurdle to safe and effective
Methods for Studying Interferon Tau Stimulated Genes
Interferon (IFN)τ, a Type I IFN produced by the conceptus trophectoderm, is the pregnancy recognition signal in ruminants that prevents development of the endometrial luteolytic mechanism. In addition, IFNτ acts in a paracrine manner
Interferon- Gene Therapy for the Treatment of Arthritis
Interferons were originally described as antiviral agents by Isaacs and Lindenmann (1 ). From its subtypes, fibroblast interferon (IFN-β) (2 ) was also found to have important cytostatic (3 ,4 ) as well as immunomodulatory functions
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