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- 2025年12月14日
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- 详细信息
- 技术资料
- 保存条件：
+4°C
- 英文名：
Mefloquine hydrochloride
- 供应商：
Hello Bio
- CAS号：
51773-92-3
- 规格：
100mg
Cx36 and Cx50 gap channel blocker (IC50 values are 0.3 and 1.1 µM, respectively). Other gap junctions (e.g. Cx43, Cx32, and Cx26) are only affected at concentrations 10-100 fold higher. In neocortical slices, mefloquine blocks gap junctional coupling between interneurons with minimal nonspecific actions.
Also shows antimalarial action. Inhibits the 80S ribosome of Plasmodium falciparum to block protein synthesis.
Additionally shows antischistosomal and antiviral actions and has recently been investigated as part of COVID-19 compound repurposing.
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Mefloquine hydrochloride
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