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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Room temperature
- 英文名:
Mifepristone
- 供应商:
Hello Bio
- CAS号:
84371-65-3
- 规格:
100mg
Potent glucocorticoid (GR) and progesterone receptor (PR) antagonist (EC50 values are 2, 10.6 and 9.5 nM at GR, PR-A and PR-B respectively). Also weakly binds the androgen receptor. Shows higher affinity for PRs than progesterone. Shows neuroprotective and antitumor effects. Active in vivo. Also used for gene editing as a mifepristone inducible Cas9 and Cpf1 CRISPR effector.
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文献和实验Characterization of Nuclear Receptor Ligands by Multiplexed Peptide Interactions
‐GHSFADPASNLGLEDIIRKALMGSF‐CONH2) (B ) in the absence or presence of 10 µM dexamethasone or mifepristone. The GR [F602S] LBD was labeled with Alexa Fluor 532. Incubation was 4 hr at room temperature. View Image
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