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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
Anti-Retinoblastoma / Rb Antibody
- 抗体英文名:
Anti-Retinoblastoma / Rb Antibody
- 浓度:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
- 应用范围:
Western Blotting: 0.5-1ug/ml IHC (FFPE): 1-2ug/ml for 30 min at RT
- 宿主:
Mouse
- 克隆性:
/
- 保存条件:
≤-20°C
- 亚型:
IgG1, kappa
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文献和实验RB基因即成视网膜细胞瘤基因,为视网膜母细胞瘤易感基因,是世界上第一个被克隆和完成全序列测定的抑癌基因。RB基因转录产物约4.7kb,表达产物为928个氨基酸组成的蛋白质,分子量约105kDa,称为P105-Rb。Rb蛋白分布于核内,是一类DNA结合蛋白。Rb蛋白的磷酸化/去磷酸化是其调节细胞生长分化的主要形式,在细胞周期的G。、G1期,它表现为去磷酸化,在G。、S、M期则处于磷酸化状态。
Purification Of Anti Peptide Antibody
antibody that could contribute to staining background. The proportion in each pool varies with the peptide immunogen. The quality of the anti-peptide serum seems to increase with multiple boosts - the first bleed may be feeble.
Analysis of E7/Rb Associations
of fundamental events, such as cell proliferation and apoptosis. The best-characterized activity of E7 from HPV type 16, the most frequently detected type in cervical cancer, is its ability to bind and induce degradation of the tumor-suppressor retinoblastoma
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