NCI-H69细胞系

NCI-H69/NCI-H69细胞系/NCI-H69细胞株/NCI-H69人小细胞肺癌细胞

Cell line name NCI-H69

Synonyms NCI-H-69; NCI H69; H69; H-69; NCIH69; NCI-HUT-69; H69/P; NCI-H69C; H69C; H69c

Accession CVCL_1579

Resource Identification Initiative To cite this cell line use: NCI-H69 (RRID:CVCL_1579)

Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Part of: COSMIC cell lines project.

Part of: MD Anderson Cell Lines Project.

Population: Caucasian.

Doubling time: 56.0 hours (PubMed=1662924).

Microsatellite instability: Stable (MSS) (Sanger).

Omics: Array-based CGH.

Omics: Deep exome analysis.

Omics: Deep proteome analysis.

Omics: Deep quantitative proteome analysis.

Omics: DNA methylation analysis.

Omics: Protein expression by reverse-phase protein arrays.

Omics: SNP array analysis.

Omics: Transcriptome analysis by microarray.

Omics: Transcriptome analysis by RNAseq.

Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.

PubMed=1662924

Khan M.Z., Freshney R.I., Murray A.M.B., Merry S., Plumb J.A., McNicol A.M.

Identification and characterisation in vitro of cells with a non-SCLC cell-like phenotype derived from a continuous SCLC cell line.

Anticancer Res. 11:1687-1695(1991)

 

PubMed=1845952; DOI=10.1002/1097-0142(19910201)67:3<619::AID-CNCR2820670317>3.0.CO;2-Y

Broers J.L.V., Mijnheere E.P., Rot M.K., Schaart G., Sijlmans A., Boerman O.C., Ramaekers F.C.S.

Novel antigens characteristic of neuroendocrine malignancies.

Cancer 67:619-633(1991)

 

PubMed=1847845; DOI=10.1007/BF00685110

Sasaki Y., Shinkai T., Eguchi K., Tamura T., Ohe Y., Ohmori T., Saijo N.

Prediction of the antitumor activity of new platinum analogs based on their ex vivo pharmacodynamics as determined by bioassay.

Cancer Chemother. Pharmacol. 27:263-270(1991)

 

PubMed=7903701; DOI=10.1093/jnci/86.2.110

Barrand M.A., Heppell-Parton A.C., Wright K.A., Rabbitts P.H., Twentyman P.R.

A 190-kilodalton protein overexpressed in non-P-glycoprotein-containing multidrug-resistant cells and its relationship to the MRP gene.

J. Natl. Cancer Inst. 86:110-117(1994)

 

PubMed=8263009; DOI=10.1007/BF01202192

Kashii T., Mizushima Y., Monno S., Nakagawa K., Kobayashi M.

Gene analysis of K-, H-ras, p53, and retinoblastoma susceptibility genes in human lung cancer cell lines by the polymerase chain reaction/single-strand conformation polymorphism method.

J. Cancer Res. Clin. Oncol. 120:143-148(1994)

 

PubMed=7736387; DOI=10.1002/1097-0142(19950515)75:10<2442::AID-CNCR2820751009>3.0.CO;2-Q

Campling B.G., Sarda I.R., Baer K.A., Pang S.C., Baker H.M., Lofters W.S., Flynn T.G.

Secretion of atrial natriuretic peptide and vasopressin by small cell lung cancer.

Cancer 75:2442-2451(1995)

 

PubMed=8626706; DOI=10.1074/jbc.271.19.11477

Quinn K.A., Treston A.M., Unsworth E.J., Miller M.-J., Vos M., Grimley C., Battey J., Mulshine J.L., Cuttitta F.

Insulin-like growth factor expression in human cancer cell lines.

J. Biol. Chem. 271:11477-11483(1996)

 

PubMed=8712684

Khan M.Z., McNicol A.M., Freshney R.I.

Tumorigenicity, invasion and metastasis of the small cell lung cancer cell line NCI-H69 and two derivative lines MOG-H69V and MOG-H69VZ.

Anticancer Res. 16:1659-1669(1996)

 

PubMed=8784480; DOI=10.1159/000227600

Shinohara A., Shimizu E., Takada M., Sone S.

Lack of c-mpl proto-oncogene transcripts and growth-stimulatory effects of thrombopoietin on human small cell lung cancer cell lines.

Oncology 53:426-434(1996)

 

PubMed=8806092; DOI=10.1002/jcb.240630505

Phelps R.M., Johnson B.E., Ihde D.C., Gazdar A.F., Carbone D.P., McClintock P.R., Linnoila R.I., Matthews M.J., Bunn P.A. Jr., Carney D.N., Minna J.D., Mulshine J.L.

NCI-Navy Medical Oncology Branch cell line data base.

J. Cell. Biochem. Suppl. 24:32-91(1996)