A20细胞

A20/A20细胞系/A20细胞株/A20小鼠B细胞淋巴瘤

Cell line name A20

Synonyms A-20

Accession CVCL_1940

Resource Identification Initiative To cite this cell line use: A20 (RRID:CVCL_1940)

Comments Part of: ENCODE project mouse cell lines.

Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).

Doubling time: 18 hours (PubMed=310843).

Omics: Array-based CGH.

Cell type: B-cell; CL=CL_0000236.

Disease Mouse reticulum cell sarcoma (NCIt: C134780)

Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)

Breed/subspecies: BALB/cAnN.

Hierarchy Children:

CVCL_YU22 (A20 NF-kappaB) CVCL_D5KA (A20-eGFP-Neo/Fluc-Puro) CVCL_QZ66 (A20-Fluc-Puro)

CVCL_C0MY (A20-Nluc-copGFP) CVCL_D138 (A20/2J) CVCL_E1J2 (HyCyte A20 KO-mCd274)

Sex of cell Sex unspecified

Age at sampling >15M

Category Cancer cell line

STR profile Source(s): PubMed=31220119; Ubigene=YC-C061

 

Markers:

Mouse STR 1-1 15,16

Mouse STR 1-2 17,18

Mouse STR 2-1 15

Mouse STR 3-2 13,14

Mouse STR 4-2 21.3

Mouse STR 5-5 14,15

Mouse STR 6-4 18

Mouse STR 6-7 11,12

Mouse STR 7-1 25.2

Mouse STR 8-1 12,13

Mouse STR 11-2 17

Mouse STR 12-1 16

Mouse STR 13-1 16.2,17.2

Mouse STR 15-3 22.3

Mouse STR 17-2 16,17

Mouse STR 18-3 15,16,18

Mouse STR 19-2 14

Mouse STR X-1 25

 

Run an STR similarity search on this cell line

Publications

PubMed=310843; DOI=10.4049/jimmunol.122.2.549

Kim K.J., Kanellopoulos-Langevin C., Merwin R.M., Sachs D.H., Asofsky R.

Establishment and characterization of BALB/c lymphoma lines with B cell properties.

J. Immunol. 122:549-554(1979)

 

PubMed=22400032; DOI=10.1155/2012/701704; PMCID=PMC3287022

Donnou S., Galand C., Touitou V., Sautes-Fridman C., Fabry Z., Fisson S.

Murine models of B-cell lymphomas: promising tools for designing cancer therapies.

Adv. Hematol. 2012:701704.1-701704.13(2012)

 

PubMed=28902524; DOI=10.1369/0022155417731319; PMCID=PMC5665108

Guja K., Liehr T., Rincic M., Kosyakova N., Hussein Azawi S.S.

Molecular cytogenetic characterization identified the murine B-cell lymphoma cell Line A-20 as a model for sporadic Burkitt's lymphoma.

J. Histochem. Cytochem. 65:669-677(2017)

 

PubMed=31220119; DOI=10.1371/journal.pone.0218412; PMCID=PMC6586308

Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B.A., Gollin S.M., Lewis D.W., Reid Y.A.

Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.

PLoS ONE 14:E0218412-E0218412(2019)