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- 武汉
- PME46587
- 2025年07月06日
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- 保存条件：
-80°C
- 保质期：
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- 英文名：
Human Estrogen Receptor beta (ESR2) (NM_001437) Protein
- 库存：
1 week
- 供应商：
缔码生物（武汉）科技有限公司
- 规格：
20 ug
| 产品类别 | ECD Proteins |
|---|---|
| 靶点 | Estrogen Receptor beta |
| Uniprot ID | Q92731 |
| 背景 | This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008] |
| 描述 | Recombinant protein of human estrogen receptor 2 (ER beta) (ESR2), full length, with C-terminal DDK tag, expressed in sf9 cells. |
| 分子量 | 59 kDa |
| 纯度 | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| 别名 | ER-BETA; Erb; ESR-BETA; ESRB; ESTRB; NR3A2; ODG8 |
| 标签 | C-DDK |
| 表达宿主 | Sf9 |
| 组分与重悬 | 50mM Tris-HCl pH8.0, 100mM glycine, 10% glycerol |
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文献和实验PPAR/ Agonist Increases the Expression of PGE2 Receptor Subtype EP4 in Human Lung Carcinoma Cells
. Peroxisome proliferator-activated receptor beta/ delta (PPARβ/δ), one of the nuclear hormone ligand-dependent transcription factors, has recently been reported to be involved in tumorigeniCity. We have shown that NSCLC cells express PPARβ/δ protein
Characterization of Nuclear Receptor Ligands by Multiplexed Peptide Interactions
., and McDonnell, D.P. 1999. Peptide antagonists of the human estrogen receptor. Science 285:744‐746. Northrop, J.P., Nguyen, D., Piplani, S., Olivan, S.E., Kwan, S.T., Go, N.F., Hart, C
Overview of Receptor Allosterism
2010 by John Wiley & Sons, Inc. Keywords: allosteric ternary complex model; bitopic; G protein?coupled receptor; modulator; orthosteric; radioligand binding
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