IL6R mouse monoclonal antibody

gene_symbol：IL6R
predicted_size：49.8 kDa
Uniprot ID：P8887
description：IL6R mouse monoclonal antibody, clone OTI2F4 (formerly 2F4)
clonality：Monoclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, May 2011]
immunogen：Full length human recombinant protein of human IL6R(NP_000556) produced in HEK293T cell.
recommended_dilution：WB 1:4000, IHC 1:150, IF 1:100
predicted_size：49.8 kDa
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
host_species：Mouse
applications：IF, IHC, WB
reactivities：Human