Purified recombinant protein o

gene_symbol：PPAR alpha
Description：Purified recombinant protein of Human peroxisome proliferator-activated receptor alpha (PPARA), transcript variant 3, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Accn：NM_001001928
Unipro ID：Q07869
Synonyms：hPPAR; NR1C1; PPAR; PPAR-alpha; PPARalpha
Species：Human
Amount：50 ug
Delivery time：4周
Expression sequence：A DNA sequence encoding human full-length PPARA
Tags：N-His
PredictedMW：52 kDa
Buffer：50 mM Tris-HCl, pH 8.0, 8 M urea
Stability：Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Bioactivity
Purity：> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration：>0.05 µg/µL as determined by microplate BCA method
Preparation
Endotoxin
Shipping
Background：Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]