Recombinant IL-1 beta (Interleukin-1 beta),Human

Recombinant IL-1 beta (Interle

ukin-1 beta),Human
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  • ¥1890
  • OriGene已认证
  • TP728234
  • 2025年11月21日
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    gene_symbol
    Description:Recombinant IL-1 beta (Interleukin-1 beta),Human
    Accn
    Unipro ID:P01584
    Synonyms:Catabolin, Lymphocyte-Activating Factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endoge_x005f_x005f_x0002_nous Mediator (LEM), Mononuclear Cell Factor (MCF)
    Species:Human
    Amount:20 ug
    Delivery time:2周
    Expression sequence:MASAPVRSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESNDKIPVALGLKEKNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAENMPVFLGGTKGGQDITDFTMQFVSS with polyhistidine tag at the C-terminus.
    Tags:His Tag (C-term)
    PredictedMW:The protein has a calculated MW of 18.5 kDa. The protein migrates as 17 kDa under reducing condition (SDS-PAGE analysis).
    Buffer:The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 8.0.
    Stability
    Bioactivity:Measure by its ability to induce IL-8 secretion in HT29 cells. The ED₅₀ for this effect is 3 x 10⁷ IU/mg.
    Purity:>98% as determined by SDS-PAGE.
    Concentration
    Preparation
    Endotoxin:<0.1 EU per 1 μg of the protein by the LAL method.
    Shipping
    Background:Interleukin-1 beta (IL-1β) is a major cytokine expressed in macrophage, NK cells, monocytes, and neutrophils. It also plays fundamental role in inflammatory response, including monocyte activation, which is essential for the host defense and pathogen and pathogen resistance. Pro-IL-1β is cleaved by cytosolic caspase 1 to form mature IL-1β.

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