Purified recombinant protein o

gene_symbol：IL12A
Description：Purified recombinant protein of Human interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) (IL12A)
Accn：NM_000882
Unipro ID：P29459
Synonyms：CLMF; IL-12A; NFSK; NKSF1; P35
Species：Human
Amount：10 ug
Delivery time：5周
Expression sequence：I23-S328; R23-S219
Tags：C-8His
PredictedMW：57.2 kDa
Buffer：Lyophilized from a 0.2 um filtered solution of PBS, pH7.5
Stability：Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Bioactivity
Purity：>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration：lot specific
Preparation
Endotoxin：Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Shipping
Background：This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]