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Recombinant Neurturin,Human

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  • ¥1890
  • OriGene已认证
  • TP728278
  • 2025年11月22日
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    gene_symbol
    Description:Recombinant Neurturin,Human
    Accn
    Unipro ID:Q99748
    Synonyms:NTN, NRTN
    Species:Human
    Amount:20 ug
    Delivery time:2周
    Expression sequence:MARLGARPCGLRELEVRVSELGLGYASDETVLFRYCAGACEAAARVYDLGLRRLRQRRRLRRERVRAQPCCRPTAYEDEVSFLDAHSRYHTVHELSARECACV with polyhistidine tag at the C-terminus.
    Tags:His Tag (C-term)
    PredictedMW:The protein has a calculated MW of 12.62 kDa. The protein migrates as 13 kDa under reducing condition (SDS-PAGE analysis).
    Buffer:The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4.
    Stability
    Bioactivity:Measure by its ability to induce proliferation in SH-SY5Y cells. The ED₅₀ for this effect is <50 ng/mL.
    Purity:>98% as determined by SDS-PAGE.
    Concentration
    Preparation
    Endotoxin:<0.1 EU per 1 μg of the protein by the LAL method.
    Shipping
    Background:Human Neurturin is a 22 kDa cytokine with 197 amino acid residues. Neurturin belongs to the same TGF-beta (transforming Growth Factors β) family. When Neurturin binds to GFRα-2 (GPI-linked receptor termed GDNF family receptor α-2), this complex activates Ret receptor tyrosine kinase and its downstream signaling pathway.

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