1-Azabicyclo[2.2.2]octane-2-ca

Synthesis of (2S, 4S, 5S)-5-(t-Butoxycarbonylamino)-4-(t-Butyldimethylsilyloxy)-2-Isopropyl-7-Methyl Octanoic Acid

In an effort to produce renm mhibttory peptides, the preparation of (2 S ,4 S ,5 S )-5-( t -Butoxycarbonylamino)-4-( t -butyldimethylsilyloxy)-2-isopropyl-7-methyl octanotc acid, 15 , was carried out ( 1 ). This pseudo-dipeptide was used

Techniques for Measuring the Activity of Carboxylic Acid:CoA Ligase and Acyl‐CoA:Amino Acid N‐Acyltransferase: The Amino Acid Conjugation Pathway

of xenobiotic carboxylic acids are metabolized to their amino acid conjugates via a pathway that exists primarily in liver and kidney. This conjugation occurs in a two?step pathway catalyzed by two distince types of enzymes, ligases and transferases

Determination of Phospholipase A2s Expression in Mast Cells by Reverse-Transcriptase Polymerase Chain Reaction

The release of arachidonic acid (AA) from membrane phospholipids by phospholipase A2 (PLA2 ) is a critical step in the generation of lipid mediators by mast cells. AA released by PLA2 activity is metabolized to bioactive compounds