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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃ to -80℃
- 保质期:
12个月
- 英文名:
Recombinant Human CD32b / FCGR2B Protein (ECD, His & AVI Tag)
- 库存:
99
- 供应商:
北京义翘神州科技股份有限公司
- 规格:
1.00 mg/50.00 µg/100.00 µg
| 规格: | 1.00 mg | 产品价格: | ¥25155.0 |
|---|---|---|---|
| 规格: | 50.00 µg | 产品价格: | ¥2310.0 |
| 规格: | 100.00 µg | 产品价格: | ¥3870.0 |
CD32B/Fcgr2b重组蛋白|Recombinant Human CD32b / FCGR2B Protein (ECD, His & AVI Tag)(产品说明)
蛋白名称:Human CD32b / FCGR2B Protein (ECD, His & AVI Tag)
蛋白构建:A DNA sequence encoding the extracellular domain (Ala 46-Ile 224) of mature human CD32b (NP_001002274.1) protein was fused with a signal peptide at the N-terminus and a c-terminal polyhistidine tagged AVI tag at the C-terminus.
表达宿主:HEK293 Cells
蛋白纯度:> 95 % as determined by SDS-PAGE
蛋白活性:1. Immobilized human CD32b-AVI-His (Cat:10259-H27H) at 10 μg/ml (100 μl/well) can bind biotinylated Human IgG1, The EC50 of biotinylated Human IgG1 is 0.20-0.48 μg/ml. 2. Using the Octet RED System, the affinity constant (Kd) of CD32B / Fcgr2b Protein, Human, Recombinant (His & AVI Tag)(Cat: 10259-H27H) bound to Herceptin was 1.5 nM.
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Ala 46
蛋白分子量:The recombinant mature human CD32b consists of 214 amino acids after proteolytic removal of the signal peptide and predicts a molecular mass of 24 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of the protein is approximately 30-35 kDa protein due to glycosylation.
蛋白NP号:NP_001002274.1
蛋白氨基酸序列:Ala46-Ile224
蛋白名称:Human CD32b / FCGR2B Protein (ECD, His & AVI Tag)
蛋白构建:A DNA sequence encoding the extracellular domain (Ala 46-Ile 224) of mature human CD32b (NP_001002274.1) protein was fused with a signal peptide at the N-terminus and a c-terminal polyhistidine tagged AVI tag at the C-terminus.
表达宿主:HEK293 Cells
蛋白纯度:> 95 % as determined by SDS-PAGE
蛋白活性:1. Immobilized human CD32b-AVI-His (Cat:10259-H27H) at 10 μg/ml (100 μl/well) can bind biotinylated Human IgG1, The EC50 of biotinylated Human IgG1 is 0.20-0.48 μg/ml. 2. Using the Octet RED System, the affinity constant (Kd) of CD32B / Fcgr2b Protein, Human, Recombinant (His & AVI Tag)(Cat: 10259-H27H) bound to Herceptin was 1.5 nM.
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Ala 46
蛋白分子量:The recombinant mature human CD32b consists of 214 amino acids after proteolytic removal of the signal peptide and predicts a molecular mass of 24 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of the protein is approximately 30-35 kDa protein due to glycosylation.
蛋白NP号:NP_001002274.1
蛋白氨基酸序列:Ala46-Ile224
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文献和实验该产品被引用文献
1, Bruggeman CW, et al. Enhanced Effector Functions Due to Antibody Defucosylation Depend on the Effector Cell Fcγ Receptor Profile.Journal of immunology (Baltimore, Md. : 1950), PubMed ID: 28566370
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CD32B/Fcgr2b重组蛋白|Recombinant Human CD32b / FCGR2B Protein (ECD, His & AVI Tag)
¥2310 - 25155








