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- 文献和实验
- 技术资料
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
- 克隆性:
Monoclonal
- 适应物种:
Human
- 保质期:
1 year
- 抗原来源:
Mouse
- 目录编号:
HV080015
- 级别:
科研级别
- 库存:
999
- 供应商:
abinscience
- 宿主:
Recombinant Human IgG Fc Fragment.
- 浓度:
1mg/ml
- 抗体英文名:
Anti-Human IgG Fc Fragment Antibody (1A043)
- 抗体名:
Anti-Human IgG Fc Fragment Antibody (1A043)
- 规格:
50ug

| Product name | Anti-Human IgG Fc Fragment Antibody (1A043) |
|---|---|
| Catalog No. | HV080015 |
| Host species | Mouse |
| Specificity | \ |
| Conjugation | \ |
| Species reactivity | Human |
| Immunogen | Recombinant Human IgG Fc Fragment. |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Purity | \ |
| Clonality | Monoclonal |
| Isotype | IgG |
| Applications | ELISA, WB |
| Target | IgG Fc Fragment |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | \ |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | \ |
| Alternative Names | \ |
| Clone ID | \ |
| Species | \ |
| Note | For research use only. |
Abinscience, founded in 2023 and located in the innovation technology center in Strasbourg, France, is the core research reagent brand of ProteoGenix. Focusing on the development and production of life science research reagents, Abinscience takes "Empowering Bioscience Discovery" as its vision, and is committed to providing high-quality and innovative biological reagent products and technical solutions for global researchers.
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文献和实验Site-Specific Chemical Modification of a Glycoprotein Fragment Expressed in Yeast
immunoglobulin G subclass 1 fragment crystallizable (IgG1 Fc), by native chemical ligation. The glycosylated IgG1 Fc is expressed in a glycosylation-deficient yeast strain. The N-terminal cysteine is generated by the endogenous yeast protease Kex2 in the yeast
FcR阻断剂,让流式实验中的干扰无处遁形 说到Fc阻断,就不得不提到抗体。抗体的结构分为Fab和Fc段,Fab段是与目标分子特异性结合的区域,Fc段是Ig与效应分子或者细胞相互作用的部位[1](图1)。Fc受体(Fragment Crystallizable Receptor,FcR)是免疫调节受体中非常重要的受体,主要在先天免疫细胞上表达,能被抗体的Fc段识别并结合,从而引发免疫应答。 图1:抗体结构 为什么要做Fc阻断? 在细胞学实验中,正确区分阳性和阴性细胞十分重要。获得良好
相关专题单克隆抗体 单克隆抗体问世以来,在临床诊断、治疗与预防等方面发挥了巨大的作用。但是常用的鼠源单克隆抗 体具有较强的免疫原性,在临床反复应用中会引起人抗鼠抗体(human anti -mouse antibody,HAMA)反应, 导致半衰期缩短,治疗效果减弱。鼠源抗体人源化是指利用DNA 重组技术和蛋白质工程技术,对抗体基 因进行重组,在保留鼠源抗体对抗原有效结合部位的同时,最大限度地降低非结合部位的鼠源性。这种通 过重组基因所表达
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