Research Grade Anti-Human EGFR
/ERBB1/HER1 (CMAB017), 研究级Anti-Human EGFR/ERBB1/HER1 (CMAB017)- ￥2588
- abinscience
- France
- HF004366
- 2026年03月03日
- Research Grade Biosimilar
- Human
- Human
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- 文献和实验
- 技术资料
- 免疫原：
Human
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
0.01M PBS,pH7.4.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
1 year
- 抗原来源：
Human
- 目录编号：
HF004366
- 级别：
科研级别
- 库存：
999
- 供应商：
abinscience
- 宿主：
Human
- 应用范围：
Research Grade Biosimilar
- 浓度：
1 mg/ml
- 靶点：
HER1, Receptor tyrosine-protein kinase erbB-1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, EGFR, ERBB1, ERBB
- 抗体英文名：
Research Grade Anti-Human EGFR/ERBB1/HER1 (CMAB017)
- 抗体名：
Research Grade Anti-Human EGFR/ERBB1/HER1 (CMAB017)
- 规格：
100ug
| Product name | Research Grade Anti-Human EGFR/ERBB1/HER1 (CMAB017) |
|---|---|
| Catalog No. | HF004366 |
| Form | Liquid |
| Storage buffer | 0.01M PBS,pH7.4. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Endotoxin level | Please contact the lab for this information. |
| Expression system | Mammalian Cells |
| Accession | P00533 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -1274°C. |
| Alternative Names | CMAB017 |
| Species | \ |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
Abinscience, founded in 2023 and located in the innovation technology center in Strasbourg, France, is the core research reagent brand of ProteoGenix. Focusing on the development and production of life science research reagents, Abinscience takes "Empowering Bioscience Discovery" as its vision, and is committed to providing high-quality and innovative biological reagent products and technical solutions for global researchers.
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文献和实验) A431 cells. At 48 h after infection, these cells were stained with ten different primary antibodies (5 g/ml) specific for different cell surface markers: anti-CD15 (clone 2F3; BD, PharMingen, San Diego, CA), anti-ERBB-2 (clone SP77; ref. 5), anti-ERBB
医学生理病理与临床分册2000，20（2）：137-140.[5]Yang XD，Jia XC，Corvalan JR， etal.Development of ABX-EGF，a fully human anti-EGF receptor monoclonal antibody，forcancertherapy.Hematology， 2001，38：17-13．[6]Herbst RS，langer CJ.Epidermal growth factor receptors as a target
从罕见病到“不限癌种”，NRG1靶点凭什么一年内连斩三大适应症？
的NRG1都含有α、β两种EGF样结构域。EGF样受体结合域是ERBB受体酪氨酸激酶活化的必要条件，位于胞外结构域的近膜区 [6]。 图1. NRG1蛋白结构示意图 *本图来源于Prolactin 出版物[6]。 NRG1主要表达于胶质细胞和神经元以及乳腺、心肌、肺、肾、肝等器官，在神经系统、心肌、乳腺发育中起重要作用 [4, 5]。有研究发现，NRG1β在神经系统、心肌细胞内表达较NRG1α高，而NRG1α在乳腺中的表达较NRG1β高 [7, 8]。此外，越来越多的研究表明NRG1融合与多种肿瘤
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