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- 文献和实验
- 技术资料
- 保存条件:
Lyophilized from a solution in 20 mM Tris-HCl pH 8.0, 100 mM NaCl,1mM EDTA, 4%trehalose,301% mannitol.
- 保质期:
1 year
- 英文名:
Recombinant Tupaia chinensis CD366/HAVCR2/TIM-3 Protein, C-Fc
- 库存:
999
- 供应商:
abinscience
- 规格:
50ug

| Product name | Recombinant Tupaia chinensis CD366/HAVCR2/TIM-3 Protein, C-Fc |
|---|---|
| Catalog No. | ZV029021 |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Purity | >90% as determined by SDS-PAGE. |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Endotoxin level | Please contact with the lab for this information. |
| Expression system | Mammalian cells |
| Accession | XP_014438264.1 |
| Protein length | Leu23-Arg194 |
| Nature | Recombinant |
| Predicted molecular weight | 47.21 kDa |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative Names | T-cell immunoglobulin mucin receptor 3, HAVcr-2, TIMD-3, T-cell membrane protein 3, HAVCR2, Hepatitis A virus cellular receptor 2, CD366, TIMD3, TIM-3, TIM3, T-cell immunoglobulin and mucin domain-containing protein 3, |
| Species | Tupaia chinensis (Chinese tree shrew) |
| Note | For research use only. |
Abinscience, founded in 2023 and located in the innovation technology center in Strasbourg, France, is the core research reagent brand of ProteoGenix. Focusing on the development and production of life science research reagents, Abinscience takes "Empowering Bioscience Discovery" as its vision, and is committed to providing high-quality and innovative biological reagent products and technical solutions for global researchers.
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文献和实验-bin/carddisp.pl?gene=HAVCR2&keywords=CD366 TIM3作为重要的细胞免疫负调控因子,高表达于辅助型T细胞(Thl细胞)和细胞毒性T细胞中(Tcl细胞),并产生抑制信号从而导致Thl细胞和Tcl细胞的凋亡。其配体为半乳凝素9(Gal-9),这是一种被广泛表达的可溶性分子[7],与TIM3分子的免疫球蛋白可变区上的寡聚糖结合,从而对Thl驱动的免疫反应产生负调控作用。当TIM3与其配体半乳凝素9(Gal-9)结合后,促进Thl细胞凋亡[8] 。也就是说
Conclusions These data demonstrate the expression of a biologically active human recombinant paraoxonase-1 protein in the mammalian cell line CHO as shown by the capacity to dephosphorylate para-nitrophenyl phosphate. The protein
-8878.3. Takayama, H. et al. 2008. High-level expression, single-step immunoaffinity purification and characterization of human tetraspanin membrane protein CD81. PLoS ONE 3: e2314 (DOI: 10.1371/journal.pone.0002314).4. Zhong, M. and Molday, R.S. 2010
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