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SN38抗体/Anti-SN38 antibody(1G1)

; Rabbit mAb
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  • 询价
  • DIMA BIOTECH/缔码生物
  • 武汉
  • DME101020
  • 2025年07月13日
  • Rabbit
  • N/A
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 亚型

      Rabbit IgG

    • 形态

      Powder

    • 保存条件

      Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    • 克隆性

      Monoclonal

    • 标记物

      Unconjugated

    • 适应物种

      N/A

    • 保质期

      12个月

    • 级别

      仅用于科研

    • 库存

      In Stock

    • 供应商

      缔码生物(武汉)科技有限公司

    • 宿主

      Rabbit

    • 靶点

      SN38

    • 抗体英文名

      Anti-SN38 antibody(1G1); Rabbit mAb

    • 抗体名

      Anti-SN38 antibody(1G1); Rabbit mAb

    • 规格

      50μg

    SKU DME101020
    产品分类 Monoclonal Antibodies
    规格 Price: 10μg ¥690.00 ; 50μg ¥2280.00 ; 100 μg ¥4080.00 ; 500 μg ¥13280.00
    背景 SN38, a potent chemotherapeutic derived from irinotecan, plays a pivotal role in colorectal cancer treatment. As the active form of irinotecan, SN38 operates as an effective DNA topoisomerase I inhibitor, inducing cell death in cancer cells. Notably, SN38's potential is harnessed in Antibody-Drug Conjugates (ADCs), where it is delivered to tumor sites through innovative methods like liposomes and nanoparticles. This targeted approach enhances SN38's efficacy, emphasizing its crucial role in ADC-based strategies for precise and potent colorectal cancer therapy.
    Clone ID 1G1
    别名 N.A.
    应用 ELISA
    形态与组成成分 Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
    纯化方式 Purified from cell culture supernatant by affinity chromatography
    反应种属 N/A
    推荐稀释比 ELISA 1:5000-10000
    靶点 SN38
    Uniprot ID N/A

    dme101020-sn38-elisa1.jpg

    Figure1. Elisa plates were pre-coated with IgG-SN38 (0.2μg/per well). Serial diluted anti-SN38 monoclonal antibody (DME101020) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-SN38 monoclonal antibody binding with IgG-SN38 is 11.39ng/ml.

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    图标文献和实验
    相关实验
    • Purification of mAb (IgG)

        Purification of mAb (IgG) by Chang-Duk Jun, 03/14/2000 Purpose Materials Antibody 7E3 , 2L sup grown in flasks, frozen and thawed overnight. BioRad Affi-Gel Protein A MAPS II Buffers

    • 祝贺〖雅裕睿安〗成为Signalway Antibody(SAB)独家

      antibody unconjugated; 货号21337,产品描述:GAPDH Antibody;规格 50 ul / 100 ul; 货号3052,产品描述:Rabbit anti-Human IgG secondary antibody HRP conjugated; 货号300904050,产品描述:One-Hour Western kit,10 ml / bottle x 3;

    • Immunocytology using the HA epitope

      . A rabbit polyclonal antisera is also available (101c500; BAbCO) but in our hands this was less reactive. The antibody cleanup protocol is now a seperate document Protocol Cells are grown in 5 mls of YPAD to an O.D. 600 of 0.75 to 1.

    图标技术资料

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