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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
Rabbit IgG
- 形态:
Powder
- 保存条件:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
N/A
- 保质期:
12个月
- 级别:
仅用于科研
- 库存:
In Stock
- 供应商:
缔码生物(武汉)科技有限公司
- 宿主:
Rabbit
- 靶点:
SN38
- 抗体英文名:
Anti-SN38 antibody(1G1); Rabbit mAb
- 抗体名:
Anti-SN38 antibody(1G1); Rabbit mAb
- 规格:
50μg
| SKU | DME101020 |
|---|---|
| 产品分类 | Monoclonal Antibodies |
| 规格 | Price: 10μg ¥690.00 ; 50μg ¥2280.00 ; 100 μg ¥4080.00 ; 500 μg ¥13280.00 |
| 背景 | SN38, a potent chemotherapeutic derived from irinotecan, plays a pivotal role in colorectal cancer treatment. As the active form of irinotecan, SN38 operates as an effective DNA topoisomerase I inhibitor, inducing cell death in cancer cells. Notably, SN38's potential is harnessed in Antibody-Drug Conjugates (ADCs), where it is delivered to tumor sites through innovative methods like liposomes and nanoparticles. This targeted approach enhances SN38's efficacy, emphasizing its crucial role in ADC-based strategies for precise and potent colorectal cancer therapy. |
| Clone ID | 1G1 |
| 别名 | N.A. |
| 应用 | ELISA |
| 形态与组成成分 | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| 纯化方式 | Purified from cell culture supernatant by affinity chromatography |
| 反应种属 | N/A |
| 推荐稀释比 | ELISA 1:5000-10000 |
| 靶点 | SN38 |
| Uniprot ID | N/A |

Figure1. Elisa plates were pre-coated with IgG-SN38 (0.2μg/per well). Serial diluted anti-SN38 monoclonal antibody (DME101020) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-SN38 monoclonal antibody binding with IgG-SN38 is 11.39ng/ml.
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文献和实验Purification of mAb (IgG) by Chang-Duk Jun, 03/14/2000 Purpose Materials Antibody 7E3 , 2L sup grown in flasks, frozen and thawed overnight. BioRad Affi-Gel Protein A MAPS II Buffers
祝贺〖雅裕睿安〗成为Signalway Antibody(SAB)独家
antibody unconjugated; 货号21337,产品描述:GAPDH Antibody;规格 50 ul / 100 ul; 货号3052,产品描述:Rabbit anti-Human IgG secondary antibody HRP conjugated; 货号300904050,产品描述:One-Hour Western kit,10 ml / bottle x 3;
Immunocytology using the HA epitope
. A rabbit polyclonal antisera is also available (101c500; BAbCO) but in our hands this was less reactive. The antibody cleanup protocol is now a seperate document Protocol Cells are grown in 5 mls of YPAD to an O.D. 600 of 0.75 to 1.
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