HEC1A细胞

HEC-1-A/HEC-1-A细胞系/HEC-1-A细胞株/HEC-1-A人子宫内膜癌细胞

Cell line name HEC-1-A

Synonyms Hec-1-A; HEC-1A; HEC1-A; HEC1A; Hec1A

Accession CVCL_0293

Resource Identification Initiative To cite this cell line use: HEC-1-A (RRID:CVCL_0293)

Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Part of: MD Anderson Cell Lines Project.

Part of: PI3K genetic alteration cell panel (ATCC TCP-1028).

Population: Japanese.

Doubling time: 31 hours (DOI=10.1007/978-4-431-53981-0_1); 27 hours (PubMed=25984343).

Microsatellite instability: Instable (MSI) (PubMed=12714694; PubMed=31068700).

Omics: Array-based CGH.

Omics: Deep exome analysis.

Omics: Deep quantitative proteome analysis.

Omics: Protein expression by reverse-phase protein arrays.

Omics: shRNA library screening.

Omics: SNP array analysis.

Omics: Transcriptome analysis by microarray.

Omics: Transcriptome analysis by RNAseq.

Derived from site: In situ; Endometrium; UBERON=UBERON_0001295.

DOI=10.1007/978-4-431-53981-0_1

Kuramoto H., Hamano M., Imai M., Fujisawa T., Kamata Y., Arai T., Kawaguchi M.

HEC-1 cells: establishment of an in vitro experimental system in endometrial carcinoma.

(In book chapter) Cell and molecular biology of endometrial carcinoma; Kuramoto H., Nishida M. (eds.); pp.3-34; Springer; Tokyo; Japan (2003)

 

PubMed=12714694; DOI=10.1093/mutage/18.3.277

Yamada N.A., Castro A., Farber R.A.

Variation in the extent of microsatellite instability in human cell lines with defects in different mismatch repair genes.

Mutagenesis 18:277-282(2003)

 

PubMed=12893190; DOI=10.1016/S0090-8258(03)00335-4

Tanaka R., Saito T., Ashihara K., Nishimura M., Mizumoto H., Kudo R.

Three-dimensional coculture of endometrial cancer cells and fibroblasts in human placenta derived collagen sponges and expression matrix metalloproteinases in these cells.

Gynecol. Oncol. 90:297-304(2003)

 

PubMed=15053063

Kamata Y., Watanabe J., Hata H., Hamano M., Kuramoto H.

Quantitative study on the correlation between p53 gene mutation and its expression in endometrial carcinoma cell lines.

Eur. J. Gynaecol. Oncol. 25:55-60(2004)

 

PubMed=15901131; DOI=10.1016/j.prp.2005.01.002

Murai Y., Hayashi S., Takahashi H., Tsuneyama K., Takano Y.

Correlation between DNA alterations and p53 and p16 protein expression in cancer cell lines.

Pathol. Res. Pract. 201:109-115(2005)

 

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662

Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.

A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.

Cancer Res. 70:2158-2164(2010)

 

PubMed=20218740; DOI=10.1177/153303461000900207; PMCID=PMC5120669

Wang Y.-M., Yang D., Cogdell D., Hu L.-M., Xue F.-X., Broaddus R., Zhang W.

Genomic characterization of gene copy-number aberrations in endometrial carcinoma cell lines derived from endometrioid-type endometrial adenocarcinoma.

Technol. Cancer Res. Treat. 9:179-189(2010)