L5178Y细胞

L5178Y TK+/- (clone 3.7.2C)细胞系、L5178Y细胞

Cell line name L5178Y TK+/- (clone 3.7.2C)

Synonyms L5178Y TK+/-3.7.2c; TK+/- (clone 3.7.2C)

Accession CVCL_6665

Resource Identification Initiative To cite this cell line use: L5178Y TK+/- (clone 3.7.2C) (RRID:CVCL_6665)

Comments Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-9518.

Doubling time: ~10 hours (Note=Lot 02052008) (JCRB=JCRB0709.1).

Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).

Derived from site: In situ; Thymus; UBERON=UBERON_0002370.

Cell type: T-cell; CL=CL_0000084.

Disease Mouse thymic lymphoma (NCIt: C134997)

Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)

Breed/subspecies: DBA/2.

Hierarchy Parent: CVCL_4235 (L-5178-Y-S)

Children:

CVCL_4W65 (L5178Y TK+/- (clone 3.7.2C) (IVGT))

Sex of cell Female

Age at sampling 8M

Category Cancer cell line

Publications

PubMed=27692294; DOI=10.1016/j.mrgentox.2016.08.001

Lorge E., Moore M.M., Clements J., O'Donovan M.R., Fellows M.D., Honma M., Kohara A., Galloway S.M., Armstrong M.J., Thybaud V., Gollapudi B.B., Aardema M.J., Tanir J.Y.

Standardized cell sources and recommendations for good cell culture practices in genotoxicity testing.

Mutat. Res. Genet. Toxicol. Environ. Mutagen. 809:1-15(2016)