K7M2 wt

K7M2-WT/K7M2-WT细胞系/K7M2-WT细胞株/K7M2-WT小鼠骨肉瘤成骨细胞

Cell line name K7M2-WT

Synonyms K7M2 wt; K7M2

Accession CVCL_V455

Resource Identification Initiative To cite this cell line use: K7M2-WT (RRID:CVCL_V455)

Comments Omics: Transcriptome analysis by microarray.

Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.

Disease Mouse osteosarcoma (NCIt: C24021)

Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)

Breed/subspecies: BALB/c.

Hierarchy Parent: CVCL_W624 (K7 [Mouse osteosarcoma])

Children:

CVCL_V454 (K7M2-pCI Neo) CVCL_XG68 (K7M3)

Sex of cell Female

Age at sampling 895D

Category Cancer cell line

Publications

PubMed=11315100; DOI=10.1023/A:1006767007547

Khanna C., Prehn J., Yeung C., Caylor J., Tsokos M.G., Helman L.J.

An orthotopic model of murine osteosarcoma with clonally related variants differing in pulmonary metastatic potential.

Clin. Exp. Metastasis 18:261-271(2000)

 

PubMed=17671136; DOI=10.1158/1078-0432.CCR-07-0313; PMCID=PMC4503209

Gordon N., Koshkina N.V., Jia S.-F., Khanna C., Mendoza A., Worth L.L., Kleinerman E.S.

Corruption of the Fas pathway delays the pulmonary clearance of murine osteosarcoma cells, enhances their metastatic potential, and reduces the effect of aerosol gemcitabine.

Clin. Cancer Res. 13:4503-4510(2007)

 

PubMed=26320182; DOI=10.18632/oncotarget.5177; PMCID=PMC4745740

Ren L., Mendoza A., Zhu J., Briggs J.W., Halsey C., Hong E.S., Burkett S.S., Morrow J.J., Lizardo M.M., Osborne T., Li S.Q., Luu H.H., Meltzer P.S., Khanna C.

Characterization of the metastatic phenotype of a panel of established osteosarcoma cells.

Oncotarget 6:29469-29481(2015)