RAMOS

Ramos/Ramos细胞系/Ramos细胞株/Ramos人B淋巴细胞瘤伯基特淋巴瘤细胞

Cell line name Ramos

Synonyms RAMOS; Ramos 1; RA 1; RA.1; Ra #1; Ra No. 1; Ramos(RA1); Ramos-RA1; Ramos (RA 1); Ramos (RA #1); Ramos (RA)

Accession CVCL_0597

Resource Identification Initiative To cite this cell line use: Ramos (RRID:CVCL_0597)

Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Part of: LL-100 blood cancer cell line panel.

Part of: MD Anderson Cell Lines Project.

Part of: NCI Pediatric Preclinical Testing Program (PPTP) cell line panel.

Population: Caucasian.

Virology: EBV-negative.

Doubling time: 20.4 +- 1.5 hours (PubMed=9225077); 23 hours (PubMed=8402660); 14 hours (PubMed=20922763); ~48 hours (DSMZ=ACC-603).

Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526).

Omics: Deep exome analysis.

Omics: Deep proteome analysis.

Omics: Protein expression by reverse-phase protein arrays.

Omics: SNP array analysis.

Omics: Transcriptome analysis by microarray.

Omics: Transcriptome analysis by RNAseq.

Derived from site: In situ; Ascites; UBERON=UBERON_0007795.

Cell type: B-cell; CL=CL_0000236.

PubMed=12967475; DOI=10.1111/j.1349-7006.2003.tb01518.x; PMCID=PMC11160262

Maesako Y., Uchiyama T., Ohno H.

Comparison of gene expression profiles of lymphoma cell lines from transformed follicular lymphoma, Burkitt's lymphoma and de novo diffuse large B-cell lymphoma.

Cancer Sci. 94:774-781(2003)

 

PubMed=18211290; DOI=10.1111/j.1365-2184.2007.00500.x; PMCID=PMC6495949

Zander Balderud L., Bemark M.

Identification of genes deregulated during serum-free medium adaptation of a Burkitt's lymphoma cell line.

Cell Prolif. 41:136-155(2008)

 

PubMed=20922763; DOI=10.1002/pbc.22801; PMCID=PMC3005554

Kang M.H., Smith M.A., Morton C.L., Keshelava N., Houghton P.J., Reynolds C.P.

National Cancer Institute pediatric preclinical testing program: model description for in vitro cytotoxicity testing.

Pediatr. Blood Cancer 56:239-249(2011)

 

PubMed=22885699; DOI=10.1038/nature11378; PMCID=PMC3609867

Schmitz R., Young R.M., Ceribelli M., Jhavar S., Xiao W.-M., Zhang M.-L., Wright G., Shaffer A.L. 3rd, Hodson D.J., Buras E., Liu X.-L., Powell J.I., Yang Y.-D., Xu W.-H., Zhao H., Kohlhammer H., Rosenwald A., Kluin P.M., Muller-Hermelink H.-K., Ott G., Gascoyne R.D., Connors J.M., Rimsza L.M., Campo E., Jaffe E.S., Delabie J., Smeland E.B., Ogwang M.D., Reynolds S.J., Fisher R.I., Braziel R.M., Tubbs R.R., Cook J.R., Weisenburger D.D., Chan W.-C., Pittaluga S., Wilson W., Waldmann T.A., Rowe M., Mbulaiteye S.M., Rickinson A.B., Staudt L.M.

Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics.

Nature 490:116-120(2012)

 

PubMed=24590883; DOI=10.1002/gcc.22161

Murga Penas E.-M., Schilling G., Behrmann P., Klokow M., Vettorazzi E., Bokemeyer C., Dierlamm J.

Comprehensive cytogenetic and molecular cytogenetic analysis of 44 Burkitt lymphoma cell lines: secondary chromosomal changes characterization, karyotypic evolution, and comparison with primary samples.

Genes Chromosomes Cancer 53:497-515(2014)

 

PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981

Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.

A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.

OncoImmunology 3:e954893.1-e954893.12(2014)

 

PubMed=25485619; DOI=10.1038/nbt.3080

Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.

A comprehensive transcriptional portrait of human cancer cell lines.

Nat. Biotechnol. 33:306-312(2015)

 

PubMed=25877200; DOI=10.1038/nature14397

Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.

A resource for cell line authentication, annotation and quality control.

Nature 520:307-311(2015)