HSP70抗体;HSP70 Polyclonal Antib

产品名称 Anti-Hsp70抗体 Hsp70 一抗 描述 小鼠单克隆抗体to Hsp70 宿主 Mouse 经测试应用 适用于: IHC-P, WB, ICC/IF, IP, Flow Cytmore details 种属反应性 与反应: Mouse, Rat, Dog, Human, African green monkey 免疫原 Recombinant fragment within Human Hsp70 aa 122-264 (N terminal). The exact sequence is proprietary. 表位 Epitope mapping with a panel of HSP 70 deletion mutants suggests that the epitope recognized is located between amino acids 122-264 of human HSP 70, a region that has been shown to be involved in ATP binding. This is the first monoclonal antibody reported to react with: 1) The ATP binding region of HSP 70. 2) An epitope in the amino terminus of HSP 70. 阳性对照 WB: HEK-293, A549, IMR-32, Jurkat, Jurkat treated with heat shock , MDCK, NIH/3T3, PC-12, COS-7, HeLa, K562, A431, U-2 OS whole cell and mouse ovary tissue lysate. IHC-P: Human prostate, tonsil and testis tissue. ICC: HeLa, NIH- 3T3, U251 MG, C6 cells. IP: HeLa cell lysates. 形式 Liquid 存放说明 Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. 存储溶液 Preservative: 0.05% Sodium azide Constituents: PBS, BSA 纯度 Protein A purified Primary antibody说明 The HSP 70 family is a set of highly conserved proteins that are induced by a variety of biological stresses, including heat stress, in every organism in which the proteins have been examined. The human HSP 70 family members include: HSP 70, a protein which is strongly inducible in all organisms but which is also constitutively expressed in primate cells; HSP 72, a 72 kDa protein that is induced exclusively under stress conditions; HSC 70, or cognate protein, is a 72 kDa, constitutively expressed, protein which is involved in the uncoating of clathrin coated vesicles; GRP 78, or BiP, is a glucose regulated 78 kDa protein localized in the endoplasmic reticulum; and p75, or HSP 75, a 75 kDa protein that is found within the mitochondria. 克隆 单克隆