HSP90β (phospho Ser226) 多克隆抗体

Signaling Events Initiated by Kappa Opioid Receptor Activation: Quantification and Immunocolocalization Using Phospho-Selective KOR, p38 MAPK, and KIR

), and causes activation of KOR. Agonist-activated KOR becomes a substrate for G protein receptor kinase (GRK), which phosphorylates the Ser369 residue at the C-terminal tail of the receptor in the first step in the β-Arrestin-dependent desensitization cascade

BCR Igα／Igβ复合物

膜上有关；后者与抗原信号传递和Ca2+流动有关。其中的极性氨基酸(Thr、Ser)与抗原识别相关分子之间形成盐键，以稳定BCR复合结构。mlg的胞内区极短，mlgM和mlgD均只有3个氨基酸残基，与T细胞中的TCR相类似，BCR需要与Iga(CD79a)和Igp(CD79b)以非共价结合形式构成复合体，共同完成对抗原的识别及信号转导。   B细胞和T细胞抗原识别结构的主要成分比较       Igα和Igβ为单链I型跨膜蛋白，分子质量分别是33kDa和37kDa，以二硫

v468 chapter 5 糖原合成酶激酶-3 的抑制

at 10, 25, and 50 μM). At 24 h post-treatment, celllysates were obtained; SDS-PAGE and Western blotting were performed as described in Section 3, Methods. AR-A014418dose-dependent decreases of phospho-β-catenin (Ser33/37) and phospho-glycogen synthase