M-CSF/ CSF1, Rat, Recombinant

M-CSF/ CSF1, Rat, Recombinant

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  • ¥1780 - 27980
  • Procell
  • PCK044
  • 武汉
  • 2025年07月15日
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    • 详细信息
    • 技术资料
    • 供应商

      武汉益普生物科技有限公司

    • 英文名

      M-CSF/ CSF1, Rat, Recombinant

    • 规格

      10μg/50ug/500ug/1mg

    规格:10μg产品价格:¥1780.0
    规格:50ug产品价格:¥4980.0
    规格:500ug产品价格:¥17480.0
    规格:1mg产品价格:¥27980.0

    产品信息

    别名Macrophage colony-stimulating factor 1; CSF-1; M-CSF; MCSF; CSF1
    物种Rat
    表达宿主Human Cells
    序列信息Glu33-Arg254
    检索号Q8JZQ0
    分子量25.2 kDa
    表观分子量46 kDa

     

    产品特性

    纯度>95% as determined by reducing SDS-PAGE.
    内毒素<1.0 EU per µg as determined by LAL test.
    保存Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输Ambient temperature or ice pack.
    制剂Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
    复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

     

    背景介绍

    Rat Macrophage colony-stimulating factor 1 (MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic Growth Factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipo Protein clearance.

    M-CSF/ CSF1, Rat, Recombinant

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