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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide of Human BCAS4
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
/
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
Q8TDM0
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA,IHC;ELISA:1:1000-1:2000,IHC:1:15-1:50
- 浓度:
>95%,Antigen affinity purification
- 靶点:
BCAS4
- 抗体英文名:
BCAS4 Antibody
- 抗体名:
BCAS4Breast carcinoma-amplified sequence 4 antibody
- 规格:
100μl/50μl
| 规格: | 100μl | 产品价格: | ¥1980.0 |
|---|---|---|---|
| 规格: | 50μl | 产品价格: | ¥1100.0 |
保存缓冲液
-20℃, pH7.4 PBS, 0.05% NaN3, 40% Glycerol功能
The gene encoding BCAS4 (Breast carcinoma-amplified sequence 4), a 211 amino acid protein, is found in a region on chromosome 20 that is frequently amplified in human breast cancer. This 20q13 locus amplification is found in 12%–39% of primary breast tumors, which correlates with a 17q23 locus amplification that is found in 20% of primary breast tumors. The amplification and translocation between the BCAS4 gene and the BCAS3 gene, with a 17q23 locus, results in a fusion transcript that is overexpressed in MCF-7 cells. Also, deletion of chromosomal region 20q13.13-q13.2 and resultant deletion of BCAS4, as well as three other genes, is the cause of Okihiro syndrome, a disease characterized by ocular and upper limb anomalies. BCAS4 is normally expressed in thymus, kidney, spleen, placenta and brain. There are three isoforms of BCAS4 which are produced as a result of alternative splicing events.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验A 腺苷脱氨酶缺乏症 adenosine deaminase deficiency (ADA) 腺病毒 adenovirus Alagille综合征 Alagille syndrome 等位基因 allele 氨基酸 amino acids 动物模型 animal model 抗体 antibody 凋亡 apoptosis 路-巴综合征 ataxia-telangiectasia 常染色体显性 autosomal dominant 常染色体 autosome B
基酸都有相对应的一个或几个对应的密码子。 动物模型animal model 定义:通过实验方法将外源基因或特定DNA片段导入实验动物中,并能够稳定的整合,从而得以有效地表达并产生相应的生理效应,该动物模型具有与人类疾病或紊乱相似的特性,从而有利于对疾病的研究。 抗体antibody 定义:在对抗原做出反应和中和时产生的血液蛋白。抗体是在对疾病的反应中产生的,能帮助机体抵抗特殊疾病。这样,抗体就获得了对疾病的免疫性。 共济失调-毛细血管扩张ataxia
catabolite repression|分解代谢物阻抑,分解代谢产物阻遏 catalase|过氧化氢酶 catalytic active site|催化活性位 catalytic activity|催化活性 catalytic antibody|催化性抗体,具有催化活性的抗体 catalytic constant|催化常数[符号Kcat] catalytic core|催化核心 catalytic
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