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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthesized peptide derived from the C-terminal region of Human TRADD.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
/
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse,Monkey
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
Q15628
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
WB, IHC, ELISA; WB:1:500-1:2000, IHC:1:100-1:300, ELISA:1:10000
- 浓度:
>95%,The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 靶点:
TRADD
- 抗体英文名:
TRADD Antibody
- 抗体名:
Tumor necrosis factor receptor type 1-associated DEATH domain protein antibody
- 规格:
100μg/50μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
保存缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.功能
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文献和实验phosphorylate IkB leading to its ubiquitination and degradation. Tumor necrosis factor (TNF) which is the best-studied activator binds to its receptor and recruits a protein called TNF receptor death domain (TRADD). TRADD binds to the TNF receptor-associated
mediated through TNF-R1 and the receptor-associated proteins, TNF-R1-associated death domain protein (TRADD) and Fas-associated death domain (FADD/MORT1) (3 –5 ). Ceramide generation and caspase activation represent potential regulation points
Biochemical Analysis of the Native TRAIL Death-Inducing Signaling Complex
The extrinsic apoptosis pathway is activated when certain members of the tumor necrosis factor (TNF) receptor superfamily (TNFRSF) are oligomerized by their cognate ligands that are members of the TNF superfamily (TNFSF). The apoptosis
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