PIK3R1抗体PIK3R1一抗抗体PtdIns-3-kin
ase regulatory subunit p85-alpha antibody抗体PIK3R1 Antibody抗体- ￥880 - 1320
- CUSABIO
- CN
- CSB-PA003765
- 2025年07月07日
- WB, IHC, ELISA; WB:1:500-1:2000, IHC:1:100-1:300, ELISA:1:40000
- Rabbit
- Human,Mouse,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Synthesized peptide derived from the Internal region of Human PI 3-kinase p85α.
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
/
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse,Rat
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
P27986
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
WB, IHC, ELISA; WB:1:500-1:2000, IHC:1:100-1:300, ELISA:1:40000
- 浓度：
>95%,The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 靶点：
PIK3R1
- 抗体英文名：
PIK3R1 Antibody
- 抗体名：
PtdIns-3-kinase regulatory subunit p85-alpha antibody
- 规格：
100μg/50μg
| 规格： | 100μg | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥880.0 |
保存缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.功能
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文献和实验Two-hybrid analysis of genetic regulatory networks
with antibodies to its epitope tag, is expressed at the same level in each diploid, and that the baits, which can be detected with anti-LexA antibody and whose DNA binding can be quantitated by a repression assay (Brent and Ptashne, 1984), occupy the operators
on the PI3K p85 regulatory subunit, or the adaptor proteins IRS1 and IRS2. IRS1 and IRS2 are phosphorylated by the activated receptor, generating docking sites for the SH2 domains of p85 and inducing proper assembly of the signalling complex. These SH2–
-α and IL-1 may constitutively stimulate the signaling pathways leading to NF-κB activation. Activation of the IKK complex either directly by HIV-1 regulatory proteins or by cytokine release leads to the phosphorylation and degradation
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