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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthesized peptide derived from Human APAF-1-ALT.
- 亚型:
/
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
/
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
O14727-6
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA,WB,IHC,IF;WB:1:500-1:3000,IHC:1:50-1:200,IF:1:100-1:200
- 浓度:
>95%,The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 靶点:
/
- 抗体英文名:
APAF1 Antibody
- 抗体名:
/
- 规格:
100μl
保存缓冲液
/功能
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.Keigo Machida, J. Biol. Chem., Apr 2001; 276: 12140 - 12146.
Liam O?鐤宱nnor, Cancer Res., Mar 2000; 60: 1217 - 1220.
Zeping Wang, Nucleic Acids Res., Apr 2005; 33: 2248 - 2258
Govindaraj Anumanthan, Cancer Res., Nov 2006; 66: 10824 - 10832.
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文献和实验该产品被引用文献
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文献支持
/抗体/兔多抗抗体/抗体APAF1 Antibody抗体
¥2024





