RUNX2抗体RUNX2兔多抗抗体SL3/AKV core-
binding factor alpha A subunit antibody抗体RUNX2 Antibody抗体- ￥440 - 1320
- CUSABIO
- CN
- CSB-PA14439A0Rb
- 2025年07月12日
- ELISA, WB; Recommended dilution: WB:1:500-1:5000
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human Runt-related transcription factor 2 protein (219-404AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
Q13950
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA, WB; Recommended dilution: WB:1:500-1:5000
- 浓度：
>95%,Protein G purified
- 靶点：
RUNX2
- 抗体英文名：
RUNX2 Antibody
- 抗体名：
SL3/AKV core-binding factor alpha A subunit antibody
- 规格：
100μg/50μg/20μg
| 规格： | 100μg | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥880.0 |
| 规格： | 20μg | 产品价格： | ￥440.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验[资源] 所有的看家基因(housekeeping genes)列表+引物设计服务
NM_004515 Homo sapiens interleukin enhancer binding factor 2, 45kDa (ILF2), mRNA 1000 NM_004651 Homo sapiens ubiquitin specific protease 11 (USP11), mRNA 1950 NM_004888 Homo sapiens ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G isoform
such as neuronal differentiation and bone loss. To produce these effects IL-6 signals through a receptor composed of two different subunits, an alpha subunit that produces ligand specificity and gp130, a receptor subunit shared in common with other cytokines
and DNA-binding of p50-RelA heterodimers is accomplished through IκBα phosphorylation and ubiquitin-dependent proteasomal degradation. Membrane-bound LTα1β2, CD40, and BAFF, on the other hand, activate via their respective receptors
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