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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human Elongation of very long chain fatty acids protein 1 protein (82-175AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
Q9BW60
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
- 浓度:
>95%,Protein G purified
- 靶点:
ELOVL1
- 抗体英文名:
ELOVL1 Antibody
- 抗体名:
ELOVL1;SSC1;CGI-88;Elongation of very long chain fatty acids protein 1;3-keto acyl-CoA synthase ELOVL1;ELOVL fatty acid elongase 1;ELOVL FA elongase 1;Very long chain 3-ketoacyl-CoA synthase 1;Very long chain 3-oxoacyl-CoA synthase 1
- 规格:
100μg/50μg/20μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
| 规格: | 20μg | 产品价格: | ¥440.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
功能
Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验or specialty scintillation proximity assay beads and the preparation of acyl carrier proteins required in other assay formats. This discontinuous assay involves the reduction of radiolabled long-chain β-ketoacyl CoA product to its dihydroxy derivative
and was resolved using electrophoresis (0.5 M urea-PAGE). Without an inhibitor the reaction was completed and produced final products of long chain (>6C) acyl-ACPs. With addition of cerulenin (200 µg/ml) or platensimycin (167 µg/ml), the reaction was blocked
Gel-elongation assay for type II fatty acid synthesis
min with or without an inhibitor, directly applied to a l6% polyacrylamide gel containing 0.5 M urea and was resolved using electrophoresis (0.5 M urea-PAGE). Without an inhibitor the reaction was completed and produced final products of long chain
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